Vilniaus universitetas

Proteomikos centras

Lietuvos biochemiku draugija

Publikacijos

  1. Jarašienė-Burinskaja R., M. Alksnė M., V. Bartuškienė, V. Voišnienė, J. Burinskij, N. Čėnas, V. Bukelskienė. 2017. Study of the cytotoxic effects of 2,5-diaziridinyl-3,6-dimethyl-1,4-benzoquinone (MeDZQ) in mouse hepatoma cells. EXCLI Journal 16: 151-159.
  2. Pečiukaitytė-Alksnė M., J. Šarlauskas, L. Misevičienė, A. Marozienė, N. Čėnas, K. Krikštopaitis, Z. Staniulytė, Ž. Anusevičius. 2017. Flavoenzyme-mediated reduction reactions and antitumor activity of nitrogen-containing tetracyclic ortho-quinone compounds and their nitrated derivatives. EXCLI Journal 16: 663-678.
  3. Smutok O., M. Karkovska, R. Serkiz, B. Vus, N. Čėnas, M. Gonchar. 2017. A novel mediatorless biosensor based on flavocytochrome b2 immobilized onto gold nanoclusters for non-invasive L-lactate analysis of human liquids. Sensors and Actuators B: Chemical 250: 469-475.
  4. Šarlauskas J., J. Tamulienė, N. Čėnas. 2017. Aziridinyl-substituted benzo-1,4-quinones: A preliminary investigation on the theoretical and experimental studies of their structure and spectroscopic properties. Spectrochimica Acta Part A-Molecular and Biomolecular Spectroscopy 178: 136-141.
  5. Urba A., D. Valiulis, J. Šarlauskas, K. Kvietkus, J. Šakalys, A. Selskis. 2017. A pilot study of different materials applied for active sampling of gaseous oxidized mercury in the atmospheric air. Atmospheric Pollution Research 8: 791-799.
  6. Valiauga B., E.M. Williams, D.F. Ackerley, N. Čėnas. 2017. Reduction of quinones and nitroaromatic compounds by Escherichia coli nitroreductase A (NfsA): Characterization of kinetics and substrate specificity. Archives of Biochemistry and Biophysics 614: 14-22.
  7. Benitez D., A. Medeiros, L. Fiestas, E. A. Panozzo-Zenere, F. Maiwald, K. C. Prousis, M. Roussaki, T. Calogeropoulou, A. Detsi, T. Jaeger, J. Šarlauskas, L. P. Mašič, C. Kunick, G. R. Labadie, L. Flohé, M.A. Comini., 2016. Identification of Novel Chemical Scaffolds Inhibiting Trypanothione Synthetase from Pathogenic Trypanosomatids. PLOS Neglected Tropical Deseases 10: e0004617
  8. Ger M., A. Kaupinis , A. Nemeikaitė-Cėnienė, J. Šarlauskas, J. Cicėnas, N. Čėnas, M. Valius. 2016. Quantitative proteomic analysis of anticancer drug RH1 resistance in liver carcinoma. Biochimica et biophysica acta: Proteins and proteomics 1864: 219-232
  9. Lesanavičius M., O. Smutok, B. Valiauga, A. Marozienė, M. Gonchar, K. Krikštopaitis, N. Čėnas. 2016. Kinetic properties of flavocytochrome b2 from Hansenula polymorpha. Chemija 27: 123-127
  10. Stulpinas A., A. Imbrasaitė, N. Krestnikova, J. Šarlauskas, N. Čėnas, A.V. Kalvelytė. 2016. Study of bioreductive anticancer agent RH-1-induced signals leading the wild-type p53-bearing lung cancer A549 cells to apoptosis. Chemical Research in Toxicology  29: 26-39
  11. Šarlauskas J., M. Pečiukaitytė-Alksnė, L. Misevičienė, A. Marozienė, E. Polmickaitė, Z. Staniulytė, N. Čėnas, Ž. Anusevičius. 2016. Naphtho[1′,2′:4,5]imidazo[1,2-a]pyridine-5,6 -diones: Synthesis, enzymatic reduction and cytotoxic activity. Bioorganic & Medicinal Chemistry Letters 26: 512-517
  12. Zor E., Y. Oztekin, A. Ramanavičienė, Ž. Anusevičius, J. Voronovic, H. Bingol, D. Barauskas-Memenas, L. Labanauskas, A. Ramanavičius. 2016. Evaluation of 1,10-phenanthroline- 5,6-dione as redox mediator for glucose oxidase Journal of Analytical Chemistry 71: 77-81
  13. Kosychova L., A. Karalius, Z. Staniulytė, R.A. Sirutkaitis, A. Palaima, A. Laurynėnas, Ž. Anusevičius. 2015. New 1-(3-Nitrophenyl)-5,6-dihydro-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepines: synthesis and computational study. Molecules 20: 5392-5408.
  14. Kosychova L., R. Vidžiūnaitė, G. Mikulskienė, I. Bratkovskaja, R. Jančienė. 2015. A convenient synthesis an spectral characterization of novel 5,6-dihydro-4H-tetrazolo-[1,5-a]benzodiazepine derivatives. ARKIVOC, 5: 71-87.
  15. Nemeikaitė-Čėnienė A., R. Jarašienė, H. Nivinskas, J. Šarlauskas, N. Čėnas. 2015. Cytotoxicity of anticancer aziridinyl-benzoquinones in murine hepatome MH22a cells: the properties of RH1-resistant subline. Chemija 26: 46-50.
  16. Šarlauskas J., A. Nemeikaitė-Čėnienė, H. Nivinskas, V. Miliukienė, R. Jarašienė, M. Pečiukaitytė, D. Baltriukienė, V. Bukelskienė, K. Krikštopaitis, N. Čėnas. 2015. Redox reactions and cytotoxicity mechanisms of anticancer aziridinyl-substituted-1,4-benzoquinones: a minireview. Chemija 26: 208-217
  17. Valiauga B., N. Rouhier, J.P. Jacquot, N. Čėnas. 2015. Quinone- and nitroreductase reactions of Thermotoga maritima thioredoxin reductase. Acta Biochimica Polonica 63: 303-309.
  18. Miliukienė V., A. Nemeikaitė-Čėnienė, N. Čėnas. 2014. Prooxidant cytotocity of polyphenolic antioxidants in primary mice splenocytes: the role of redox potential and lipophilicity. Chemija 25: 218-223.
  19. Miliukienė V., H. Nivinskas, N. Čėnas. 2014. Cytotoxicity of anticancer aziridinyl-substituted benzoquinones in primary mice splenocytes. Acta Biochimica Polonica 61: 833-836.
  20. Nivinskas H., B. Valiauga, J. Šarlauskas, N. Čėnas. 2014. Reduction of aziridinyl-substituted anticancer benzoquinones by lipoamide dehydrogenase. Chemija 25: 213-217
  21. Šarlauskas J., L. Misevičienė, A. Marozienė, L. Karvelis, J. Stankevičiūtė, K. Krikštopaitis, N. Čėnas, A. Yantsevich, A. Laurynėnas, Ž. Anusevičius. 2014. The study of NADPH-dependent flavoenzyme-catalyzed reduction of benzo[1,2-c]1,2,5-oxadiazole N-oxides (benzofuroxans). International Journal of Molecular Sciences 15: 23307-23331.
  22. Zor E., Y. Oztekin, L. Mikoliunaite, J. Voronovic, A. Ramanaviciene, Ž. Anusevicius, H. Bingol, A. Ramanavicius. 2014. 1,10-Phenanthroline-5,6-dione and 9,10-phenanthrenequinone as redox mediators for amperometric glucose biosensors. Journal of Solid State Electrochemistry 18: 1529-1536.
  23. Zor E., Y. Oztekin, A. Ramanaviciene, Ž. Anusevicius, H. Bingol, J. Barkauskas, M. Ersoz, A. Ramanavicius. 2014. Amperometric glucose biosensor based on glucose oxidase, 1,10-Phenanthroline-5,6-dione and carbon nanotubes. Journal of the Electrochemical Society 161: H3064-H3069.
  24. Anusevičius Ž., H. Nivinskas, J. Šarlauskas, M.-A. Sari, J.-L. Boucher, N. Čėnas. 2013. Single-electron reduction of quinone and nitroaromatic xenobiotics by recombinant rat neuronal nitric oxide synthase. Acta Biochimica Polonica 60: 217-222.
  25. Krikštopaitis K., L. Misevičienė, Ž. Anusevičius, S. Zeman, A. Elbeih, N. Čėnas, H. Nivinskas, V. Miliukienė, M. Talaikis, J. Šarlauskas. 2013. Cyclic nitroamines: investigation of their electrochemical properties, cytotoxicity and enzymatic reactions. Proceedings of the 16th Seminar on New Trends in Research of Energetic Materials. p. 735-743.
  26. Šarlauskas J., A. Nemeikaitė-Čėnienė, L. Misevičienė, K. Krikštopaitis, Ž. Anusevičius, N. Čėnas. 2013. Redox properties and prooxidant cytotoxicity of a neuroleptic agent 6,7-dinitrodihydroquinoxaline-2,3-dione (DNQX). Acta Biochimica Polonica 60: 227-231.
  27. Šarlauskas J. 2013. Preparation and properties of 6,7,8,9-tetranitro-3,4-dihydro-2H-1,5-benzodiazepine (TNDX), a potential new high energy material. Proceedings of the 16th Seminar on New Trends in Research of Energetic Materials. 2013. p. 915-926.
  28. Anusevičius Ž., L. Misevičienė, J. Šarlauskas, N. Rouhier, J. P. Jacquot, N. Čėnas. 2012. Quinone- and nitroreductase reactions of Thermotoga maritima peroxiredoxin–nitroreductase hybrid enzyme. Arhives of Biochemistry and Biophysics 528: 50-56.
  29. Labanauskas L., V. Dudutiene, G. Urbelis, J. Šarlauskas, J. Sudzius, D. Matulis, R. Striela, A. Zilinskas. 2012. Synthesis of substituted 2l4d2-[1,2,3]thiadiazolo[3,4-c]benzimid-azoles and 2λ4δ2-[1,2,3,5]thiatriazolo[3,4-c]benzimidazoles. ARKIVOC viii: 17-26.
  30. Marozienė A., A. Nemeikaitė-Čėnienė, R. Vidžiūnaitė, N. Čėnas. 2012. Correlation between mammalian cell cytotoxicity of flavonoids and the redox potential of phenoxyl radical/phenol couple. Acta Biochimica Polonica 59: 299-305.
  31. Miliukienė V., J. Šarlauskas, K. Krikštopaitis, A. Šaikūnas, N. Čėnas. 2012. Possible modes of cytotoxicity of high energy aliphatic nitroesters and N-nitramines for mouse splenocytes. Chemija 23: 141-146.
  32. Šarlauskas J., Z. Anusevičius, A. Misiūnas. 2012. Benzofuroxan (Benzo[1,2-c]1,2,5-oxadiazole N-oxide) derivatives as potential energetic materials: studies on their synthesis and properties. Central European Journal of Energetic Materials 9: 273-290.
  33. Šarlauskas J. 2012. Some derivatives of benzofuroxan (Benzo[1,2-c]1,2,5-oxadiazole N-oxide): recent studies on the synthesis and properties. Proceedings of the 15th Seminar on New Trends in Research of Energetic Materials. 2012. p. 780-789.
  34. Maroziene A., A. Nemeikaite-Ceniene, N. Cenas. 2011. Studies of quinone cytotoxicity mechanisms: determination of quinone / semiquinone redox couple potential according to quinone-mediated ascorbate oxidation kinetics. Chemija 22: 162-166.
  35. Miseviciene L., Z. Anusevicius, J. Sarlauskas, I.F. Sevrioukova, N. Cenas. 2011. Redox reactions of the FAD-containing apoptosis-inducing factor (AIF) with quinoidal xenobiotics: A mechanistic study. Archives of Biochemistry and Biophysics 512: 183-189.
  36. Rouhier N., J.P. Jacquot, L. Misevičienė, Ž. Anusevičius, J. Šarlauskas, N.Čėnas. 2011. Two-electron reduction of nitroaromatic compounds by Thermotoga maritima hybrid peroxiredoxin–nitroreductase enzyme. Chemija 22: 143-148.
  37. Sarlauskas J., K. Krikstopaitis, V. Miliukiene, N. Cenas, Z. Anusevicius and A. Saikunas. 2011. Investigation on the electrochemistry and cytotoxicity of organic nitrates and nitroamines. Central European Journal of Energetic Materials 8: 15-24.
  38. Grellier P., A. Maroziene, H. Nivinskas, J. Sarlauskas, A. Aliverti, N. Cenas. 2010. Antiplasmodial activity of quinones: Roles of aziridinyl substituents and the inhibition of Plasmodium falciparum glutathione reductase. Archives of Biochemistry and Biophysics 494: 32-39.
  39. Venskutonis P.R., V. Dedonyte, J. Lazutka, G. Slapsyte, A. Maroziene, A. Nemeikaite-Ceniene, N. Cenas, G. Miliauskas. 2010. A preliminary assessment of singlet oxygen scavenging, cytotoxic and genotoxic properties of Geranium macrorrhizum extracts. Acta Biochimica Polonica 57: 157-163.
  40. Šarlauskas J. Polynitrobenzenes containing alkoxy and alkylenedioxy groups: Potential HEMs and precursors of new energetic materials. Central European Journal of Energetic Materials. 2010. Vol. 7, p. 115-129.
  41. Šarlauskas J. Polynitroderivatives of alkoxy- and alkylendioxy-benzenes: potential HEMs and precursors of new energetic materials. Proceedings of Seminar on New Trends in Research of Energetic Materials. 2010. Vol. 11, p. 720-729.
  42. Šarlauskas J. Synthesis of energetic materials containing benzimidazole core. Proceedings of Seminar on New Trends in Research of Energetic Materials. 2010. Vol. 11, p. 730-737.
  43. Šarlauskas J., K. Krikštopaitis, V. Miliukienė, Ž. Anusevičius, A. Šaikūnas, N. Čėnas. Organic nitrates and nitramines: synthesis, electrochemistry and cytotoxicity. Proceedings of Seminar on New Trends Res. Energetic Materials. 2010. Vol. 11, p. 738-744.
  44. Dolidze A., R. Chedia, N. Kavtaradze, L. Misevičienė, V. Miliukienė, A. Nemeikaitė-Čėnienė, N. Čėnas. 2009. Redox properties of chrysanthemic acid esters of hydroxynaphthoquinones: implications for their toxicity in mammalian cells. Chemija 20: 116-119.
  45. Šarlauskas J., V. Miliukienė, Ž. Anusevičius, L. Misevičienė, K. Krikštopaitis, A. Nemeikaitė-Čėnienė, I. Vitėnienė, N. Čėnas. 2009. Redox properties and prooxidant cytotoxicity of benzofuroxans: a comparison with nitrobenzenes. Chemija 20: 109-115.
  46. Grellier P., A. Nemeikaitė-Čenienė, J. Šarlauskas, N. Čėnas. 2008. Role of single-electron oxidation potential and lipophilicity in the antiplasmodial in vitro activity of polyphenols: Comparison to mammalian cells. Zeitschrift fur Naturforschung Section C-A Journal of Biosciences 63: 445-450
  47. Miliukienė V., N. Čėnas. 2008. Cytotoxicity of nitroaromatic explosives and their biodegradation products in mice splenocytes: Implications for their immunotoxicity. Zeitschrift fur Naturforschung Section C-A Journal of Biosciences 63: 519-525.
  48. Nivinskas, H., J. Šarlauskas, Ž. Anusevičius, H.S. Toogood, N.S. Scrutton, N. Čėnas. 2008. Reduction of aliphatic nitroesters and N-nitramines by Enterobacter cloacae PB2 pentaerythritol tetranitrate reductase: quantitative structure-activity relationships. FEBS J. 275: 6192-6203
  49. Anestål, K., S. Prast-Nielsen, N. Čėnas, E.S. Arner. 2008. Cell death by SecTRAPs: thioredoxin reductase as a prooxidant killer of the cells. PLoS ONE, 3: e1846.
  50. Anestål, K., S. Prast-Nielsen, E.S.J. Arner, H. Nivinskas, J. Šarlauskas, A. Marozienė, N. Čėnas. 2008. Reactions of mammalian thioredoxin reductase with quinoidal and nitroaromatic xenobiotics: mechanisms, specific role of selenocysteine, and implications for cytotoxicity. Flavins and Flavoproteins, 16: 487-495.
  51. Šarlauskas, J., H. Nivinskas, Ž. Anusevičius, A. Nemeikaitė-Čėnienė, H.S. Toogood, N.S. Scruton, P. Montrimas, N. Čėnas. 2008. QSARs in the reductive denitration of organic nitrate and N-nitramine explosives by E. cloacae PB2 PETN reductase. New Trends Res. Energ. Materials, 11: 755-760.